• Topic: Mitochondria and Diseases
• Proposed Issue: Volume 46, No. 2, February 2025
• Range: Any topics related to mitochondria and diseases
• Submission: Mark the submission with “Mitochondria and Diseases” Thematic Issue at the top of the title page
• Limitations: No
• Guest Editor: Stefan Kohring, PhD, Molecular Medicine, Georg-August-Universität Göttingen, Germany

Mitochondria play a critical role in the human body as they are responsible for generating most of the cell's supply of adenosine triphosphate (ATP), which is essential for cellular energy production. When mitochondria become dysfunctional, it can lead to a wide range of diseases and disorders due to impaired energy production and oxidative stress. Cumulative evidence shown that mitochondrial dysfunction is implicated in various conditions such as neurodegenerative diseases, metabolic disorders, cardiovascular diseases, and even cancer. Factors such as genetic mutations, environmental toxins, poor diet, and aging can all contribute to mitochondrial dysfunction. Understanding the link between mitochondria and disease pathology is crucial for developing targeted treatments and interventions to improve patient outcomes.