Published May 5, 2021

Eva Grand

Heather Mossel  


Keratoconjunctivitis sicca, also known as dry eye disease, is an inflammatory condition of the ocular surface caused by a pathologic reduction in the aqueous component of the tear film. Keratoconjunctivitis sicca usually manifests as dry eyes, foreign bodies, burning, itching, blurred vision, red eyes, and contact lens intolerance. In the reported epidemiological investigations, the global prevalence of keratoconjunctivitis sicca was 5%-50% due to different populations and diagnostic criteria. Wearing contact lenses can aggravate symptoms. This paper reviews the research progress of keratoconjunctivitis sicca.



Keratoconjunctivitis Sicca, Epidemiology, Symptoms, Therapy, Prognosis

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How to Cite
Grand, E., & Mossel, H. (2021). On the Keratoconjunctivitis Sicca. Science Insights, 37(1), 271–276. https://doi.org/10.15354/si.21.re061