Published Dec 31, 2022

Jung Heo  


Frailty, as a type of geriatric condition, has been a major focus of geriatrics researchers in recent years. COPD is one of the major risk factors associated with frailty. Consequently, chronic obstructive pulmonary disease-related frailty has become the focal point of numerous investigations. However, the majority of studies focus on cross-sectional investigations of the incidence of frailty in COPD and their associations. The study of its pathophysiology and intervention methods is dispersed, and there is a paucity of literature reviews. Moreover, in-depth research into the pathophysiology of such patients and the implementation of efficient therapeutic strategies are crucial for enhancing the long-term quality of life of patients. The purpose of this article is to provide a reference for creating nutritional intervention programs for chronic obstructive pulmonary disease and a debilitated population by describing the etiology of these patients and summarizing potential nutritional therapies based on recent research.



Lung Disease, Chronic Obstructive Pulmonary Disease, Frailty, Pathogenesis, Intervention

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How to Cite
Heo, J. (2022). Pathogenesis and Nutritional Intervention of Chronic Obstructive Pulmonary Disease-Associated Frailty. Science Insights, 41(7), 761–767. https://doi.org/10.15354/si.22.re105